Increase in Invasive Group a Streptococcal Infections in Children in the Netherlands, A Survey Among 7 Hospitals in 2022

Author:

van Kempen Evelien B.1ORCID,Bruijning-Verhagen Patricia C. J.2,Borensztajn Dorine34,Vermont Clementien L.5,Quaak Marjolijn S. W.5,Janson Jo-Anne6,Maat Ianthe7,Stol Kim8,Vlaminckx Bart J. M.9,Wieringa Jantien W.10,van Sorge Nina M.1112ORCID,Boeddha Navin P.3,van Veen Mirjam1

Affiliation:

1. Department of Paediatrics, Juliana Children’s Hospital, Haga Hospital, The Hague

2. Department of Paediatrics, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht

3. Department of Paediatrics, Maasstad Ziekenhuis, Rotterdam

4. Department of Paediatrics, Noordwest Ziekenhuisgroep, Alkmaar & Den Helder

5. Department of Paediatrics, Division of Paediatric Infectious Diseases & Immunology, Erasmus MC-Sophia Children’s Hospital, University Medical Center Rotterdam, Rotterdam

6. Department of Paediatrics, Maastricht University Medical Center+, Maastricht

7. Department of Microbiology, Radboud University Medical Center, Nijmegen

8. Department of Paediatrics, Division of Paediatric Infectious Diseases & Immunology, Amalia Children’s Hospital, Radboud University Medical Center, Nijmegen

9. Department of Microbiology, St. Antonius Hospital, Nieuwegein

10. Department of Paediatrics, Haaglanden Medical Center, The Hague

11. Department of Medical Microbiology and Infection Prevention, Amsterdam UMC location University of Amsterdam, Amsterdam

12. Netherlands Reference Center for Bacterial Meningitis, Amsterdam UMC location AMC, Amsterdam, The Netherlands.

Abstract

Following an increase in notifiable invasive group A streptococcal (iGAS) infections in the Netherlands, we conducted a survey among 7 hospitals. Pediatric iGAS case numbers were 2-fold higher between July 2021 and June 2022 versus pre-COVID-19. A sharp increase occurred early 2022, most pronounced in <5 years old and for diagnoses empyema and necrotizing fasciitis. This recent pediatric iGAS surge warrants investigation and vigilance.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Infectious Diseases,Microbiology (medical),Pediatrics, Perinatology and Child Health

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