Trend in the Numbers of Hospitalized Patients With Varicella, Herpes Zoster, and Ischemic Stroke in Japanese Individuals <20 Years of Age Before and After Implementation of Universal Varicella Vaccination

Author:

Ishimaru Soichiro1,Michihata Nobuaki2,Kawamura Yoshiki1ORCID,Uda Kazuaki3,Matsui Hiroki4,Fushimi Kiyohide5,Yasunaga Hideo4,Yoshikawa Tetsushi1

Affiliation:

1. Department of Pediatrics, Fujita Health University School of Medicine, Toyoake, Japan

2. Department of Health Services Research, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

3. Health Services Research and Development Center, University of Tsukuba, Tsukuba, Japan

4. Department of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo, Japan

5. Department of Health Policy and Informatics, Tokyo Medical and Dental University Graduate School of Medicine, Tokyo, Japan.

Abstract

Several studies have shown an association between varicella-zoster virus infection and ischemic stroke. We analyzed the trends in the numbers of patients with varicella, herpes zoster and ischemic stroke before and after the universal vaccination program using a Japanese database of hospitalized patients. The number of patients with varicella decreased but those of herpes zoster and ischemic stroke did not change.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Infectious Diseases,Microbiology (medical),Pediatrics, Perinatology and Child Health

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