COVID-19 Vaccine Acceptance Among Parents of Children With Multisystem Inflammatory Syndrome in Children

Author:

Blanchard-Rohner Geraldine1ORCID,Sanchez Carlos2,Andre Maya C.34,Bressieux-Degueldre Sabrina5,Grazioli Serge6,Perez Marie-Helene7,Wütz Daniela8,Schöbi Nina9,Welzel Tatjana210,Atkinson Andrew211,Schlapbach Luregn J.1213,Bielicki Julia A.14,Trück Johannes15,

Affiliation:

1. From the Division of General Pediatrics, Department of Child, Woman and Adolescent Medicine, Pediatric Immunology and Vaccinology Unit, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland

2. Paediatric Research Centre, University Children’s Hospital Basel, University of Basel, Basel, Swizerland

3. Division of Respiratory and Critical Care Medicine, University Children’s Hospital Basel, University of Basel, Basel, Switzerland

4. Department of Pediatric Hematology and Oncology, University Children’s Hospital, Eberhard Karls University, Tuebingen, Germany

5. Department of Women-Mother-Child, Paediatric Cardiology Unit, University Hospital of Lausanne and Lausanne University, Lausanne, Switzerland

6. Division of Neonatal and Pediatric Intensive Care, Department of Child, Woman and Adolescent Medicine, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland

7. Department of Women-Mother-Child, Paediatric Intensive and Intermediate Care Units, University Hospital of Lausanne and Lausanne University, Lausanne, Switzerland

8. Division of Pediatric Cardiology, Pediatric Heart Center, University Children’s Hospital Zurich, Zurich, Switzerland

9. Division of Pediatric Infectious Diseases, Department of Pediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland

10. Division of Pediatric Rheumatology, University Children’s Hospital Basel, University of Basel, Basel, Switzerland

11. Division of Infectious Diseases, Washington University in St. Louis School of Medicine, St. Louis, Missouri

12. Department of Intensive Care and Neonatology, Children`s Research Center, University Children’s Hospital Zurich, Zurich, Switzerland

13. Paediatric Intensive Care Unit, Child Health Research Centre, Queensland Children’s Hospital, The University of Queensland, Brisbane, Australia

14. Centre for Neonatal and Paediatric Infection, St George’s University, London, United Kingdom

15. Divisions of Allergy and Immunology, Children’s Research Center, University Children’s Hospital Zurich, University of Zurich (UZH), Zurich, Switzerland.

Abstract

Data on COVID-19 vaccine acceptability among parents of children with multisystem inflammatory syndrome (MIS-C) are limited. In this cohort of children with MIS-C, enrolled in the Swissped RECOVERY trial (NCT 04826588), comparing intravenous immunoglobulins or methylprednisolone, who, in accordance with Swiss guidelines, were recommended for SARS-CoV-2 vaccination, 65% (73/112) of parents reported being vaccinated against SARS-CoV-2 before the MIS-C, while 70% were vaccinated after the MIS-C episode of their child. None of the children were vaccinated before the occurrence of the MIS-C, and only 9% (5/56) received the COVID-19 vaccine after the MIS-C. The predominant barriers to COVID-19 vaccination were concerns over potential side effects and insufficient support from their doctors. This emphasizes the crucial role of health care providers in promoting COVID-19 vaccination among children.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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