Has COVID-19 Changed Pediatric Acute Rhinosinusitis Epidemiology During the First 2 Pandemic Years?

Author:

Hazan Itai1ORCID,Ziv Oren23,Marom Tal234ORCID,Zloczower Elchanan35ORCID,Pitaro Jacob36ORCID,Warman Meir35ORCID

Affiliation:

1. Joyce and Irvin Goldman Medical School, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheba, Israel

2. Division of Otorhinolaryngology, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheba, Israel

3. Clalit Health Services, Tel Aviv, Israel

4. Department of Otolaryngology-Head and Neck Surgery, Samson Assuta Ashdod University Hospital, Ashdod, Israel

5. Department of Otorhinolaryngology, Head and Neck Surgery, Kaplan Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel

6. Department of Otolaryngology-Head and Neck Surgery, Shamir Medical Center (formerly Assaf Harofeh), Zerifin, Israel, affiliated to the Sackler School Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Abstract

Objective: To study national pediatric acute rhinosinusitis (ARS) burden fluctuations before and during the first 2 coronavirus-19 (COVID) years, characterized by alternating lockdown and relaxation periods, the introduction of COVID vaccines, and the emergence of nonalpha COVID variants. Methods: This was a cross-sectional, population-based study covering the 3 pre-COVID years and the first 2 COVID years from a big database of the largest Israeli Health Maintenance Organization. For comparison purposes, we explored ARS burden trends with those of urinary tract infection (UTI), which is unrelated to viral diseases. We identified children <15 years presenting with ARS and UTI episodes and categorized them according to their age and presentation date. The average ARS and UTI episodes of the 3 pre-COVID years were used to calculate the incidence rate ratios (IRRs) of the 2 COVID years, analyzed separately. Seasonal variations were explored. Results: We identified 44,483 ARS and 121,263 UTI episodes. There was a substantial reduction in ARS episodes during the COVID years (IRR 0.36, 95% CI: 0.24–0.56, P < 0.001). Although UTI episode rates also decreased during COVID (IRR 0.79, 95% CI: 0.72–0.86, P < 0.001), the reduction in ARS burden was 3-fold higher. The dominant pediatric ARS age group was between 5 and 15 years. The largest decrease in ARS burden was during the first COVID year. ARS episode distribution showed a seasonal fluctuation, with a peak during the summer months during the COVID years. Conclusions: Pediatric ARS burden decreased during the first 2 COVID years. Episode distribution was noted to be year-round.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Infectious Diseases,Microbiology (medical),Pediatrics, Perinatology and Child Health

Reference17 articles.

1. Clinical and Virological Characteristics of Acute Sinusitis in Children.;DeMuri;Clin Infect Dis,2019

2. Pediatric Sinusitis.;Zacharisen;Immunol Allergy Clin North Am,2005

3. Pediatric rhinosinusitis.;Magit;Otolaryngol Clin North Am,2014

4. Development, structure and function of the upper airways.;Pohunek;Paediatr Respir Rev,2004

5. Anatomic variations of the paranasal sinuses in the general pediatric population.;Cohen;Rhinology,2019

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