Human Parechovirus Central Nervous System Infection in a Young Infant Cohort

Author:

Katragkou Aspasia12ORCID,Sheth Avni3,Gagliardo Christina12,Aquino Jessica4,Shah Niva3,Nwaobasi-Iwuh Eberechi3,Melchionne Christina4,Black Paige3,Chiu Stephanie5,Di Pentima Cecilia12

Affiliation:

1. Infectious Diseases Division, Department of Pediatrics, Atlantic Health System, Goryeb Children's Hospital, Morristown, New Jersey

2. Department of Pediatrics, Sidney Kimmel Medical College of Thomas Jefferson University[aff_start], [/aff_end]Philadelphia, Pennsylvania

3. Department of Pediatrics

4. Emergency Department, Atlantic Health System, Goryeb Children's Hospital, Morristown, New Jersey

5. Atlantic Center for Research, Atlantic Health System[aff_start], [/aff_end]Morristown, New Jersey.

Abstract

In 2022, a surge in cases of pediatric human parechovirus (HPeV) central nervous system infections in young infants was seen at our institution. Despite the dramatic increase in the number of cases seen that year, the clinical features of the illness were similar to prior years. The recent pediatric HPeV surge highlights the need to evaluate treatment options and standardize follow-up to better understand the long-term prognosis of infants with HPeV infection.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Infectious Diseases,Microbiology (medical),Pediatrics, Perinatology and Child Health

Reference10 articles.

1. Human parechovirus: an increasingly recognized cause of sepsis-like illness in young infants.;Olijve;Clin Microbiol Rev,2017

2. Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support.;Harris;J Biomed Inform,2009

3. Human parechoviruses: biology, epidemiology and clinical significance.;Harvala;J Clin Virol,2009

4. Lessons from SARS-CoV-2 pandemics: how restrictive measures impacted the trend of respiratory infections in neonates and infants up to three months of age.;De Rose;Pathogens,2022

5. Increased detection of human parechovirus infection in infants in England during 2016: epidemiology and clinical characteristics.;Ferreras Antolin;Arch Dis Child,2018

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