How to ventilate critically ill children with cancer?: a narrative review

Author:

Domínguez-Rojas Jesús1ORCID,Torres Godoy Silvio Fabio2,Mora Robles Lupe Nataly3,Méndez Aceituno Alejandra4

Affiliation:

1. Pediatric Intensive Care Unit, Emergency and Critical Areas Department, National Institute of Children’s Health, Lima, Peru

2. Pediatric Intensive Care Unit, Austral University Hospital, Pilar, Argentina

3. Pediatric Intensive Care Unit, José Carrasco Arteaga Hospital, Cuenca, Ecuador

4. Evat Multisite Project (Global Critical Care), Department of Global Pediatric Medicine, St. Jude Children´s Research Hospital, Memphis, TN, USA.

Abstract

Abstract The management of respiratory failure and hypoxemia in children with cancer presents a critical challenge. Choosing between invasive and noninvasive mechanical ventilation can profoundly impact mortality rates, especially in resource-limited settings. Choosing between invasive and noninvasive mechanical ventilation can impact mortality rates, particularly in resource-limited settings. Extensive clinical studies are imperative to thoroughly evaluate the efficacy of invasive mechanical ventilation (IMV) and noninvasive ventilation (NIV) during the early stages of treatment. Further research is crucial to determine the most optimal therapeutic approach. Early implementation of IMV or NIV could significantly reduce mortality rates in these patients.[ 1 ] Additionally, this article examines the admission of children with terminal cancer, evaluating their use of invasive and noninvasive ventilatory support versus palliative care. The interdisciplinary medical team, in collaboration with the family, must carefully consider the benefits and risks of these interventions, whether in the early or terminal stages of the disease. Furthermore, the article delves into the controversies surrounding the utilization of ventilation in critically ill children with cancer.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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