Outcomes of Geriatric Periprosthetic Distal Femur Fractures: Comparison of Fixation Versus Reconstruction

Author:

Joseph Noah M.1ORCID,Zuke William2,Sharpe Megan1,Bacharach Abigail1,Punjabi Nihal1,Zhao Chenya3,Sattar Abdus3,Emara Ahmed K.2,Piuzzi Nicolas S.2,Ochenjele George1,Patterson Brendan M.2,Vallier Heather A.1

Affiliation:

1. Department of Orthopaedics, Case Western Reserve University School of Medicine, Cleveland, OH;

2. Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH; and

3. Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH.

Abstract

Objective: Comparing outcomes of periprosthetic distal femur fractures treated with open reduction and internal fixation (ORIF) versus distal femoral replacement (DFR). Setting: Three major academic hospitals within one metropolitan area. Design: Retrospective. Patients/Participants: Three hundred seventy patients >64 years old with periprosthetic distal femur fractures were identified and 115 were included (65 ORIF vs. 50 DFR). Intervention: ORIF with locked plating versus DFR. Main Outcome Measurement: One-year mortality, ambulatory status at 1 year, reoperations, and hospital readmissions. Results: No differences were observed between ORIF and DFR cohorts regarding demographics or medical history, including Charleston Comorbidity Index. DFR was associated with longer hospital stay (6.09 days ORIF vs. 9.08 days DFR, P < 0.001) and more frequent blood transfusion (12.3% ORIF vs. 44.0% DFR, P < 0.001). Logistic regression analysis using propensity score matching (PSM) demonstrated no statistically significant difference in reoperation, hospital readmission, ambulatory status at 1 year, or 1-year mortality between the 2 cohorts. Finally, applying Bayesian model averaging using PSM to identify risk factors for 1-year mortality demonstrated that increasing age, length of index hospital stay, and 90-day hospital readmission were significantly associated with 1-year mortality, regardless of type of surgical treatment. Conclusion: Rehospitalization, reoperation, ambulatory status, and 1-year mortality are no different between ORIF and DFR in the treatment of geriatric periprosthetic distal femur fractures when PSM is applied to mitigate selection bias. Further study is warranted to elucidate functional outcomes, long-term sequelae, and costs of care related to these treatment options to better guide treatment planning. Level of Evidence: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Orthopedics and Sports Medicine,General Medicine,Surgery

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