The association of opium with coronary artery disease

Author:

Sadeghian Saeed1,Darvish Soodabeh1,Davoodi Gholamreza1,Salarifar Mojtaba1,Mahmoodian Mehran1,Fallah Nader2,Karimi Abbas Ali1

Affiliation:

1. Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran

2. Department of Biostatistics, Shahed University, Tehran, Iran

Abstract

Background The effects of opium consumption on coronary artery disease are still unknown. Methods A cross-sectional study was conducted on 2405 patients admitted to the Angiographic Ward at Tehran Heart Center from 7 May 2005 to 13 August 2005. Results After adjusting for conventional cardiovascular risk factors, opium consumption was a significant risk factor for coronary artery disease ( P=0.01 and odds ratio = 1.8). Moreover, the amount of opium consumption was associated significantly with the severity of coronary atherosclerosis, as measured by clinical vessel score ( r=0.2, P=0.002). Conclusions To our knowledge, this is the first time that the adverse effects of opium consumption on coronary arteries was defined. Eur J Cardiovasc Prev Rehabil14:715-717 © 2007 The European Society of Cardiology

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine,Epidemiology

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