Lenalidomide Consolidation Added to Rituximab Maintenance Therapy in Patients Remaining PET Positive After Treatment for Relapsed Follicular Lymphoma: A Phase 2 Australasian Leukaemia & Lymphoma Group NHL26 Study

Author:

Trotman Judith12,Presgrave Peter3,Carradice Duncan P.4,Lenton Douglas Stuart56,Gandhi Maher K.78,Cochrane Tara910,Badoux Xavier11,Carlson Julia12,Nkhoma Gloria12,Butcher Belinda1113,Nikpour Armin214,Fulham Michael214,Johnston Anna M.1516

Affiliation:

1. Haematology, Concord Repatriation General Hospital, University of Sydney, Concord, NSW, Australia

2. University of Sydney, Camperdown, NSW, Australia

3. Department of Haematology, Wollongong Hospital, NSW, Australia

4. Department of Haematology and Medical Oncology, Western Health and University of Melbourne, St Albans, VIC, Australia

5. Orange Hospital, NSW, Australia

6. University of Sydney, Orange, NSW, Australia

7. Princess Alexandra Hospital, Brisbane, QLD, Australia

8. Mater Research University of Queensland, Brisbane, QLD, Australia

9. Department of Haematology, Gold Coast University Hospital, Southport, Australia

10. Griffith University, Southport, Australia

11. University of New South Wales, Sydney, NSW, Australia

12. Australasian Leukaemia and Lymphoma Group, Richmond, VIC, Australia

13. WriteSource Medical Pty Ltd, Lane Cove, NSW, Australia

14. Department of Molecular Imaging, Royal Prince Alfred Hospital, Camperdown, NSW, Australia

15. Department of Hematology, Royal Hobart Hospital, Hobart, TAS, Australia

16. University of Tasmania, Hobart, TAS, Australia

Publisher

Wiley

Subject

Hematology

Reference12 articles.

1. Update: the investigation and management of follicular lymphoma.;McNamara;Br J Haematol,2020

2. Role of imaging in the staging and response assessment of lymphoma: consensus of the International Conference on Malignant Lymphomas Imaging Working Group.;Barrington;J Clin Oncol,2014

3. Response-adapted postinduction strategy in patients with advanced-stage follicular lymphoma: the FOLL12 study.;Luminari;J Clin Oncol,2022

4. Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide.;Lopez-Girona;Leukemia,2012

5. Immunomodulatory drugs stimulate natural killer-cell function, alter cytokine production by dendritic cells, and inhibit angiogenesis enhancing the anti-tumour activity of rituximab in vivo.;Reddy;Br J Haematol,2008

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