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Targeting CD133high Colorectal Cancer Cells In Vitro and In Vivo With an Asymmetric Bispecific Antibody

  • Published:2015-07 Issue:6 Volume:38 Page:217-228
  • ISSN:1524-9557
  • Container-title:Journal of Immunotherapy
  • language:en
  • Short-container-title:

Author:

Zhao Lei,Yang Yudan,Zhou Pengfei,Ma Hong,Zhao Xiaolai,He Xin,Wang Tao,Zhang Jing,Liu Yang,Zhang Tao

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cancer Research,Pharmacology,Immunology,Immunology and Allergy

Reference6 articles.

1. Cancer statistics, 2015.;Siegel;CA Cancer J Clin,2015

2. Cancer stem cells, tumor dormancy, and metastasis.;Patel;Front Endocrinol Lausanne,2012

3. Daoy medulloblastoma cells that express CD133 are radioresistant relative to CD133 cells, and the CD133 sector is enlarged by hypoxia.;Blazek;Int J Radiat Oncol Biol Phys,2007

4. Bispecific T-cell engaging antibodies for cancer therapy.;Baeuerle;Cancer Res,2009

5. Knobs-into-holes engineering of antibody CH3 domains for heavy chain heterodimerization.;Ridgway;Protein Eng,1996

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