CYP3A5 genotype has significant effect on quinine 3-hydroxylation in Tanzanians, who have lower total CYP3A activity than a Swedish population-Reference-Cited by-同舟云学术

CYP3A5 genotype has significant effect on quinine 3-hydroxylation in Tanzanians, who have lower total CYP3A activity than a Swedish population

Published:2006-09 Issue:9 Volume:16 Page:637-645
ISSN:1744-6872
Container-title:Pharmacogenetics and Genomics
language:en
Short-container-title:

Author:

Mirghani Rajaa A.,Sayi Jane,Aklillu Eleni,Allqvist Annika,Jande Mary,Wennerholm Agneta,Eriksen Jaran,Herben Virginie M.M.,Jones Barry C.,Gustafsson Lars L.,Bertilsson Leif

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Genetics (clinical),Genetics,Molecular Biology,Molecular Medicine,General Pharmacology, Toxicology and Pharmaceutics

Reference54 articles.

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5. Enzyme kinetics for the formation of 3-hydroxyquinine and three new metabolites of quinine in vitro; 3-hydroxylation by CYP3A4 is indeed the major metabolic pathway;Mirghani;Drug Metab Dispos,2002

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