Thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase expression in colorectal cancer and normal mucosa in patients

Author:

Amatori Federica,Di Paolo Antonello,Del Tacca Mario,Fontanini Gabriella,Vannozzi Francesca,Boldrini Laura,Bocci Guido,Lastella Marianna,Danesi Romano

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Genetics (clinical),Genetics,Molecular Biology,Molecular Medicine,General Pharmacology, Toxicology and Pharmaceutics

Reference25 articles.

1. Phase III multicenter randomized trial of oxaliplatin added to chronomodulated fluorouraci lleucovorin as first-line treatment of metastatic colorectal cancer;Giacchetti;J Clin Oncol,2000

2. Different lengths of a polymorphic repeat sequence in the thymidylate synthase gene affect translational efficiency but not its gene expression;Kawakami;Clin Cancer Res,2001

3. Thymidylate synthase expression in colorectal cancer: a prognostic and predictive marker of benefit from adjuvant fluorouracil-based chemotherapy;Edler;J Clin Oncol,2002

4. Polymorphism in the thymidylate synthase promoter enhancer region in colorectal cancer;Marsh;Int J Oncol,2001

5. Polymorphisms of the repeated sequences in the enhancer region of the thymidylate synthase gene promoter may predict downstaging after preoperative chemoradiation in rectal cancer;Villafranca;J Clin Oncol,2001

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