High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1)

Author:

Niemi Mikko,Schaeffeler Elke,Lang Thomas,Fromm Martin F,Neuvonen Mikko,Kyrklund Carl,Backman Janne T,Kerb Reinhold,Schwab Matthias,Neuvonen Pertti J,Eichelbaum Michel,Kivistö Kari T

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

General Pharmacology, Toxicology and Pharmaceutics,Genetics

Reference54 articles.

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3. Disposition of pravastatin sodium, a tissue-selective HMG-CoA reductase inhibitor, in healthy subjects.;Singhvi;Br J Clin Pharmacol,1990

4. Biliary excretion of pravastatin in rats: contribution of the excretion pathway mediated by canalicular multispecific organic anion transporter (cMOAT).;Yamazaki;Drug Metab Dispos,1997

5. Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance.;Konig;Biochim Biophys Acta,1999

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