Efavirenz Induces CYP2B6-Mediated Hydroxylation of Bupropion in Healthy Subjects

Author:

Robertson Sarah M,Maldarelli Frank,Natarajan Ven,Formentini Elizabeth,Alfaro Raul M,Penzak Scott R

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Pharmacology (medical),Infectious Diseases

Reference35 articles.

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2. Development of a substrate-activity based approach to identify the major human liver P-450 catalysts of cyclophosphamide and ifosfamide activation based on cDNA-expressed activities and liver microsomal P-450 profiles.;Roy;Drug Metab Dispos,1999

3. Role of hepatic and intestinal cytochrome P450 3A and 2B6 in the metabolism, disposition, and miotic effects of methadone.;Kharasch;Clin Pharmacol Ther,2004

4. Sertraline is metabolized by multiple cytochrome P450 enzymes, monoamine oxidases, and glucuronyl transferases in human: an in vitro study.;Obach;Drug Metab Dispos,2005

5. CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes.;Ramirez;Drug Metab Dispos,2004

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