Performance and Interpretation of Lung Scintigraphy-Reference-Cited by-同舟云学术

Performance and Interpretation of Lung Scintigraphy

Published:2024-09-07 Issue: Volume: Page:
ISSN:1536-0229
Container-title:Clinical Nuclear Medicine
language:en
Short-container-title:Clin Nucl Med

Author:

Le Pennec Romain¹,Schaefer Wolfgang²,Tulchinsky Mark³,Lamoureux François⁴,Roach Paul⁵,Rischpler Christoph⁶,Zukotynski Katherine⁷,O’Brien Christopher⁸,Murphy Declan⁵,Pascal Pierre⁹,Le Gal Grégoire¹⁰,Salaun Pierre-Yves¹,Le Roux Pierre-Yves¹

Affiliation:

1. Univ Brest, CHU Brest, Médecine Nucléaire, GETBO, UMR1304, Brest, France

2. Department of Nuclear Medicine, Maria Hilf Hospital, Mönchengladbach, Germany

3. Division of Nuclear Medicine, Department of Radiology, Penn State University, Hershey, PA

4. Hôpital de Val D'Or, Val D'Or, Quebec, Canada

5. Royal North Shore Hospital, Sydney, Australia

6. Department of Nuclear Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

7. Departments of Radiology and Medicine, McMaster University, Hamilton, Ontario, Canada

8. Nuclear Medicine, Brantford General Hospital, Brantford, Ontario, Canada

9. Médecine Nucléaire, CHU Toulouse, Toulouse, France

10. Department of Medicine, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.

Abstract

Purpose Although ventilation/perfusion (V/Q) scintigraphy is a widely used imaging test, different options are possible for the acquisition and interpretation of the scan. The aim of this study was to assess current practices regarding the use and interpretation of lung scintigraphy in various clinical indications. Patients and Methods An online survey comprising 25 questions was sent to nuclear medicine departments in Australia, Canada, France, Germany, and United States between 2022 and 2023. A single response per department was consolidated. Results Four hundred nineteen responses were collected (Australia: 32, Canada: 58, France: 149, Germany: 92, and United States: 88). For acute pulmonary embolism (PE) diagnosis, 82.8% of centers reported using SPECT acquisitions (Australia: 93.3%, Canada: 91.8%, France: 99.2%, Germany: 96.2%, and United States: 32.1%). Among them, SPECT images were combined with a CT scan in 70.5% of centers. A total of 10.6% of centers reported not using ventilation for acute PE diagnosis. SPECT acquisition was used in 97.8% of centers using 99mTc carbon particles, 97.1% 81mKr gas, 58.7% 99mTc-DTPA, and 19.4% 133Xe gas, respectively. For V/Q SPECT interpretation, the EANM criteria were used in 65.0% of departments. A very wide variety of practices were observed in pregnant women and in COVID-19 patients. SPECT acquisition was widely used in the follow-up of PE and for the screening of chronic thromboembolic pulmonary hypertension (>90% of centers), with inconsistency regarding the interpretation of matched perfusion defects in this setting. Conclusions This survey shows the strong adoption of SPECT in the various clinical indications of lung scintigraphy, except in the United States, where planar imaging is still mostly used. The survey also shows variability in interpretation criteria both for PE diagnosis and screening for chronic thromboembolic pulmonary hypertension, highlighting the need for further standardizations of practices.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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