68Ga-FAPI PET/CT Imaging

Author:

Al-Ibraheem Akram,Abdlkadir Ahmed Saad1,Alalawi Hasan1,Badarneh Mohannad1

Affiliation:

1. Department of Nuclear Medicine and PET/CT, King Hussein Cancer Center

Abstract

Abstract 68Ga-FAPI has been introduced recently in many nuclear medicine centers. Many pitfalls have been discussed previously. However, not all pitfalls are currently addressed in the literature. To our knowledge, this is the first reported case to address nonspecific 68Ga-FAPI expression at anorectal sphincter. A 69-year-old woman was diagnosed with intrahepatic cholangiocarcinoma. A 68Ga-FAPI scan was performed after diagnostic workup and chemoradiotherapy. In addition to 68Ga-FAPI–avid lesion at primary site, several nononcological ancillary findings have been observed. This includes unaddressed 68Ga-FAPI–avid focus within anorectal sphincter. Moreover, the same noteworthy findings were observed in the musculoskeletal and gynecological systems.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Radiology, Nuclear Medicine and imaging,General Medicine

Reference9 articles.

1. 68Ga-FAPI PET/CT: tracer uptake in 28 different kinds of cancer;J Nucl Med,2019

2. 68Ga-FAPI PET/CT provides a clear picture of a Klatskin tumor that 18 F-FDG PET/CT missed;Clin Nucl Med,2023

3. Impact of (68)Ga-FAPI PET/CT imaging on the therapeutic management of primary and recurrent pancreatic ductal adenocarcinomas;J Nucl Med,2021

4. Uterine uptake of 68Ga-FAPI-04 in uterine pathology and physiology;Clin Nucl Med,2022

5. 68Ga-DOTA-FAPI-04 PET/CT as a promising tool for differentiating ovarian physiological uptake: preliminary experience of comparative analysis with 18F-FDG;Front Med (Lausanne),2021

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