68Ga-DOTATATE PET/CT of Metastatic Lymphoepithelial Carcinoma of Parotid Gland

Author:

Low Han Chung1,Loke Kelvin Siu Hoong1,Wang Fu Qiang2,Han Shuting3,Nei Wen Long2

Affiliation:

1. Department of Nuclear Medicine and Molecular Imaging, Singapore General Hospital

2. Radiation Oncology

3. Medical Oncology, National Cancer Centre Singapore, Singapore.

Abstract

Abstract We present a case of a 59-year-old woman with lymphoepithelial carcinoma of left parotid gland. She was treated with radical radiotherapy, but her plasma Epstein-Barr virus DNA load continued to increase despite good locoregional response. As her primary tumor was positive for somatostatin receptor type 2, we performed 68Ga-DOTATATE PET/CT, which revealed multiple DOTATATE-avid distant metastases.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Radiology, Nuclear Medicine and imaging,General Medicine

Reference8 articles.

1. Lymphoepithelial carcinoma of salivary glands;Surg Pathol Clin,2021

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3. Somatostatin receptor 2 expression in nasopharyngeal cancer is induced by Epstein Barr virus infection: impact on prognosis, imaging and therapy;Nat Commun,2021

4. (68)Ga-DOTA-peptide: a novel molecular biomarker for nasopharyngeal carcinoma;Head Neck,2016

5. Somatostatin receptor imaging with [68Ga]Ga-DOTATATE positron emission tomography/computed tomography (PET/CT) in patients with nasopharyngeal carcinoma;Eur J Nucl Med Mol Imaging,2022

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