18F-FDOPA PET/CT of Paraganglioma in the Spermatic Cord

Author:

Goujon Anna1,Pop Gabriel2,Hissier Julien3,Moreau Benjamin4,Palard-Novello Xavier5

Affiliation:

1. Urology

2. Pathology

3. Radiology

4. Endocrinology, CHU Rennes

5. Department of Nuclear Medicine, Univ Rennes, CLCC Eugène Marquis, INSERM, Rennes, France.

Abstract

Abstract A 53-year-old man with chronic kidney failure was referred to perform an 18F-FDOPA PET/CT to characterize a mass located on the right spermatic cord. Previously, the pathological analysis of CT-guided biopsies suggested paraganglioma or metastatic lesion of pheochromocytoma. Serum normetanephrine and serum metanephrine values were respectively 2- and 1.5-fold greater than the normal upper limit, which could be explained by the chronic kidney failure. PET/CT images revealed intense 18F-FDOPA uptake of the mass without any other pathological findings, suggesting the diagnosis of paraganglioma. Pathological examination of surgical specimen confirmed the diagnosis of paraganglioma of the spermatic cord, which is exceptional.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Radiology, Nuclear Medicine and imaging,General Medicine

Reference10 articles.

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2. Neurogenic tumors in the abdomen: tumor types and imaging characteristics;Radiographics,2003

3. Genitourinary paraganglioma: demographic, pathologic, and clinical characteristics in the surveillance, epidemiology, and end results database (2000–2012);Urol Oncol,2017

4. Paraganglioma of the spermatic cord: report of one case and review of literature;Int J Clin Exp Pathol,2020

5. Phaeochromocytoma of the spermatic cord: report of a case;J Pathol,1971

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