Mismatch Between Brain MRIs and 18F-DOPA PET/CT

Author:

Bourbonne Vincent,Dissaux Brieg,Seizeur Romuald,Nguyen Jessica1,Querellou Solène

Affiliation:

1. Medical Oncology

Abstract

Abstract After receiving erlotinib for 4 years, a man with advanced lung adenocarcinoma was treated with stereotactic radiotherapy for a left cerebellar brain metastasis. Local relapse of the metastasis was suspected 14 months after and confirmed on 18F-DOPA PET. Three additional uptakes were described with no unequivocal MRI pathological signal. A second radiotherapy course was delivered. One year later, isolated local recurrence was suspected on a 3 T MRI, with a suspicious 18F-DOPA uptake. Five additional 18F-DOPA uptakes were described among which one increased between the 2 PETs. Because of these MRI/PET mismatches, a switch from erlotinib to osimertinib was preferred over surgery.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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