Comparison of the 68Ga-FAPI Versus 18F-FDG in Gastric Adenocarcinoma and Anthracosis-Associated Lymph Nodes: FAPI Unmasking False-Negatives and False-Positives-Reference-Cited by-同舟云学术

Comparison of the 68Ga-FAPI Versus 18F-FDG in Gastric Adenocarcinoma and Anthracosis-Associated Lymph Nodes: FAPI Unmasking False-Negatives and False-Positives

Published:2024-01-23 Issue:3 Volume:49 Page:e134-e136
ISSN:1536-0229
Container-title:Clinical Nuclear Medicine
language:en
Short-container-title:Clin Nucl Med

Author:

Babacan Gündüzalp Buğrahan¹,Öner Tamam Müge¹,Şengiz Erhan Selma²,Şahin Mehmet Can¹,Acar Tayyar Merve Nur¹

Affiliation:

1. Nuclear Medicine

2. Pathology, Prof. Dr. Cemil Taşcıoğlu City Hospital, Hamidiye Faculty of Medicine, Health Science University, İstanbul, Turkey.

Abstract

Abstract A 73-year-old woman with poorly differentiated gastric adenocarcinoma was referred to 18F-FDG PET/CT for evaluation of the disease. FDG PET/CT showed intense uptake in the disseminated lymph nodes. However, there was no uptake in the primary tumoral lesion. Subsequently, 68Ga-FAPI-04 PET/CT was performed with the decision of the tumor board and demonstrated intense uptake in the tumoral lesion. However, there was low or no uptake in disseminated lymph nodes. Tru-cut biopsy results revealed that all the lymph nodes were associated with anthracosis.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Reference15 articles.

1. False positive F-18 FDG PET/CT in neck and mediastinum lymph nodes due to anthracosis in a buccal cancer patient;Clin Nucl Med,2011

2. The curious case of the black buboes;Cureus,2022

3. Fibroblast activation protein inhibitor imaging in nonmalignant diseases: a new perspective for molecular imaging;J Nucl Med,2022

4. Pitfalls and common findings in 68Ga-FAPI PET: a pictorial analysis;J Nucl Med,2022

5. False-positive 68Ga-fibroblast activation protein-specific inhibitor uptake of benign lymphoid tissue in a patient with breast cancer;Clin Nucl Med,2021