Uncommon Manifestation of Oligometastatic Prostate Cancer

Author:

Luna Cibele1,Kryvenko Oleksandr N.,Martinez Jose,Singal Rakesh2,Kuker Russ1

Affiliation:

1. Division of Nuclear Medicine, Department of Radiology, Jackson Memorial Hospital, University of Miami

2. Division of Medical Oncology, Department of Medicine, Sylvester Comprehensive Cancer Center, Miami, FL.

Abstract

Abstract A 76-year-old man with a history of prostate cancer diagnosed in 2008 developed biochemical recurrence in 2010 and started intermittent androgen deprivation therapy. In 2021, due to rising prostate-specific antigen, an 18F-piflufolastat PSMA PET/CT was performed. It showed a radiotracer-avid sclerotic lesion in the right iliac bone and an indeterminate radiotracer-avid nodule in the umbilical region, demonstrating progressive enlargement and increased uptake on subsequent imaging. Pathologic analysis of the umbilical nodule revealed metastatic prostate cancer—a finding eponymically referred to as a Sister Mary Joseph nodule.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Radiology, Nuclear Medicine and imaging,General Medicine

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