First Experience of Radionuclide Therapy With 177Lu-FAPI-2286 in a Patient With Metastatic Mediastinal Sarcoma

Author:

Banihashemian Seyedeh Somayyeh1,Bayat Mohadese2,Pirayesh Elahe2,Divband Ghasemali3,Abolhosseini Abdolghafar4,Akbari Mohammad Esmaeel1

Affiliation:

1. Cancer Research Center, Shahid Beheshti University of Medical Sciences

2. Department of Nuclear Medicine, Shohada Tajrish Medical Center, School of Medicine, Shahid Beheshti University of Medical Sciences

3. Khatam PET-CT Center, Khatam-al-Anbia Hospital

4. Parsisitope Company, Tehran, Iran.

Abstract

Abstract Fibroblast activation protein (FAP) is a new promising molecular target for theragnostic approach. FAP inhibitors (FAPIs) labeled with 177Lu could be potentially a therapeutic radiopharmaceutical. Here, we presented the experience of 4 cycles of 177Lu-FAPI in a 67-year-old man with an unresectable mediastinal sarcoma.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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