Apparently Benign 131I Adrenal Uptake-Reference-Cited by-同舟云学术

Apparently Benign 131I Adrenal Uptake

Published:2024-08-02 Issue: Volume: Page:
ISSN:1536-0229
Container-title:Clinical Nuclear Medicine
language:en
Short-container-title:Clin Nucl Med

Author:

Travaglio Morales Daniela¹,Kreissl Michael C.²,Fischer Florian¹,Heinzel Alexander¹

Affiliation:

1. Nuclear Medicine Department, University Hospital Halle, Halle (Saale)

2. Division of Nuclear Medicine, Department of Radiology and Nuclear Medicine, University Hospital Magdeburg, Magdeburg, Germany.

Abstract

Abstract A 60-year-old man suffering from papillary thyroid cancer (pT2 pN0(0/21) cM0) underwent diagnostic 131I whole-body scintigraphy with recombinant thyroid-stimulating hormone for follow-up after thyroidectomy and adjuvant 131I therapy with 4.2 GBq. A focal uptake of radioiodine was found in the right adrenal gland, which had not been seen on the initial posttherapeutic images; therefore, an adrenal metastasis was suspected. However, the diagnostic workup including contrast-enhanced MRI as well as endocrine laboratory tests indicated a benign etiology showcasing a very rare case of false-positive radioiodine uptake in the adrenal gland. The imaging follow-up after 1 year showed no significant changes.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Reference9 articles.

1. Unusual metastases from differentiated thyroid cancers: a multicenter study in Korea;PloS One,2020

2. Isolated adrenal metastases of papillary thyroid carcinoma;Endokrynol Pol,2022

3. Adrenocortical adenoma manifesting as false-positive iodine accumulation in a patient with history of thyroid carcinoma;Radiol Case Rep,2018

4. Structural insights into the mechanism of the sodium/iodide symporter;Nature,2022

5. Sodium/iodide symporter: a key transport system in thyroid cancer cell metabolism;Eur J Endocrinol,1999