18F-Florbetapir PET/CT and 68Ga-FAPI PET/CT in a Case of Light Chain Amyloidosis With Predominant Multiple Tumor-Like Deposits-Reference-Cited by-同舟云学术

18F-Florbetapir PET/CT and 68Ga-FAPI PET/CT in a Case of Light Chain Amyloidosis With Predominant Multiple Tumor-Like Deposits

Published:2024-03-06 Issue:5 Volume:49 Page:486-488
ISSN:1536-0229
Container-title:Clinical Nuclear Medicine
language:en
Short-container-title:Clin Nucl Med

Author:

Zhang Yuke¹,Wang Xuezhu¹,Ren Chao¹,Shen Kaini²,Huo Li¹

Affiliation:

1. Nuclear Medicine

2. Hematology, Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, State Key Laboratory of Complex Severe and Rare Diseases, Center for Rare Diseases Research, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Abstract

Abstract A 66-year-old man presented with multiple masses in different regions, including the left groin, back subcutaneous area, and lungs. Pathological examination confirmed localized amyloid deposits after 3 surgeries. Serum-free λ light chains were elevated. To evaluate systemic involvement, the patient underwent 18F-Florbetapir PET/CT and 68Ga-FAPI-04 PET/CT. Both scans showed increased uptake in multiple masses and nodules throughout the body. This report presents a rare case of light chain (AL) amyloidosis, primarily characterized by multiple localized tumor-like deposits with high activity on 18F-Florbetapir PET/CT and 68Ga-FAPI-04 PET/CT.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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