Novel Diagnostic Imaging Approach for Patients With Spontaneous Coronary Artery Dissection

Author:

Safiullah Zaid N.1,Latina Jacqueline M.2,Ziogos Efthymios2,Harb Tarek2,Schindler Thomas H.3,Valenta-Schindler Ines3,Alavi Abass4,Gerstenblith Gary2,Leucker Thorsten M.2

Affiliation:

1. Department of Medicine

2. Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD

3. Mallinckrodt Institute of Radiology, Division of Nuclear Medicine, Cardiovascular Medicine, Washington University School of Medicine, St Louis, MO

4. Department of Radiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

Abstract

Abstract Spontaneous coronary artery dissection (SCAD) is an underdiagnosed etiology of acute coronary syndrome in women. Accurate diagnosis remains challenging but is imperative for treatment and prevention. We show here the utility of 18F-FDG PET imaging in SCAD diagnosis. We present 1 representative case of 4 women with suspected SCAD on coronary angiography from the EVACS (Evolocumab in Acute Coronary Syndromes) clinical trial. 18F-FDG PET imaging showed acute inflammation in the distribution of the suspected dissected coronary artery identified on angiography. Localized myocardial inflammation identified on 18F-FDG PET imaging can aid in diagnosing SCAD suspected on coronary angiography.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Radiology, Nuclear Medicine and imaging,General Medicine

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