68Ga-PSMA and 68Ga-FAPI-04 PET/CT Findings With 18F-FDG PET/CT in a Patient With Recurrent Prostate Cancer

Author:

Tatar Gamze1,Ergül Nurhan2,Baloğlu Mehmet Can2,Arslan Esra2,Çermik Tevfik Fikret2

Affiliation:

1. University of Health Sciences, Department of Nuclear Medicine, Istanbul Bagcilar Training and Research Hospital

2. University of Health Sciences, Clinic of Nuclear Medicine, Istanbul Training and Research Hospital, Istanbul, Turkey.

Abstract

Abstract A 79-year-old man with prostate cancer was evaluated with 68Ga–prostate-specific membrane antigen (PSMA), 68Ga-FAPI-04, and 18F-FDG PET/CT scans since a rise in prostate-specific antigen was seen at last control while receiving chemotherapy. Abnormal FDG uptakes were observed in the tumoral areas of the left half of the prostate and walls of the bladder, although PSMA and FAPI activity were absent or lower in the relevant tumoral areas. Restaging 68Ga-PSMA and 18F-FDG PET/CT scans were obtained on the patient whose progression continued after transurethral tumor resection. Herein, we present a case proving intraindividual tumor heterogeneity in prostate cancer underwent PET/CT imaging with 3 different radiopharmaceuticals.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Radiology, Nuclear Medicine and imaging,General Medicine

Reference10 articles.

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