18F-THK5351 PET Can Evaluate Tumor Extension in Intravascular Large B-Cell Lymphoma-Reference-Cited by-同舟云学术

18F-THK5351 PET Can Evaluate Tumor Extension in Intravascular Large B-Cell Lymphoma

Published:2023-01-20 Issue:4 Volume:48 Page:e204-e206
ISSN:1536-0229
Container-title:Clinical Nuclear Medicine
language:en
Short-container-title:Clin Nucl Med

Author:

Hatano Keiko¹,Ishibashi Kenji,Kondo Soichiro¹,Ishii Kenji,Iwata Atsushi²

Affiliation:

1. Department of Neurology, TokyoMetropolitan Geriatric Hospital, Tokyo, Japan

2. Research Team for Neuroimaging, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan.

Abstract

Abstract A 79-year-old man presenting with gait disturbance and cognitive decline was diagnosed with intravascular large B-cell lymphoma (IVLBCL) by random skin biopsy. Some IVLBCL lesions were identified by PET examinations using 11C-methionine, 18F-FDG, and 18F-THK5351. 11C-methionine and 18F-FDG uptake, which likely reflects the presence of the lymphoma cells themselves, increased clearly in the left putamen but weakly in the left deep white matter. 18F-THK5351 uptake increased in all lesions, likely reflecting perivascular astrogliosis caused by IVLBCL. Hence, 18F-THK5351 PET can evaluate tumor extension in IVLBCL lesions where 11C-methionine and 18F-FDG PET may fail in its visualization.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Radiology, Nuclear Medicine and imaging,General Medicine

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