Prostate-Specific Membrane Antigen PET Positivity in a Lung Mass

Author:

Caputo Sydney A.1,Jang Albert2,Talbert Joshua3,Saba Nakhle S.,Sartor Oliver

Affiliation:

1. Tulane University School of Medicine

2. Deming Department of Medicine

3. Department of Radiology, Tulane University School of Medicine

Abstract

Abstract An 84-year-old man with nonmetastatic castrate-sensitive prostate cancer was referred for a 68Ga–prostate-specific membrane antigen (PSMA) PET/CT scan with a prostate-specific antigen level of 3.6 ng/mL for restaging. He was 22 years post–radical prostatectomy and had salvage radiation being managed with intermittent hormonal therapy. Imaging revealed a right lower lobe mass with increased PSMA uptake (SUVmax 6.2). Biopsy and subsequent immunostaining determined the mass to be diffuse large B-cell lymphoma. We report a case of diffuse large B-cell lymphoma diagnosed in the setting of PSMA positivity, highlighting awareness for oncologists and radiologists to know this possibility.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Radiology, Nuclear Medicine and imaging,General Medicine

Reference9 articles.

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3. Prostate-specific membrane antigen uptake in small cleaved B-cell follicular non-Hodgkin lymphoma;Clin Nucl Med,2016

4. Concomitant prostate carcinoma and follicular lymphoma: “flip-flop” appearances on PSMA and FDG PET/CT scans;Clin Nucl Med,2019

5. Follicular lymphoma showing avid uptake on 68Ga PSMA-HBED-CC PET/CT;Clin Nucl Med,2016

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