Somatostatin Receptor PET Imaging in Diffuse Pancreatic Neuroendocrine Tumor

Author:

Zhao Qian1,Dong Aisheng2,He Tianlin3,Zuo Changjing2

Affiliation:

1. Department of Nuclear Medicine, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China

2. Nuclear Medicine

3. Hepatopancreatobiliary Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.

Abstract

Abstract Somatostatin receptor imaging findings of pancreatic neuroendocrine tumor with diffuse involvement of the pancreas are rarely reported. We present somatostatin receptor PET imaging findings in 3 cases of diffuse pancreatic neuroendocrine tumor. One case showed diffuse swelling and diffusely intense activity of the pancreas with multiple metastases in the peripancreatic lymph nodes and liver. The other 2 cases showed diffusely intense activity of the pancreas without metastasis. The pancreatic tumor extended into the duodenum in all the 3 cases. Familiarity with this rare pattern of radiotracer uptake in pancreatic neuroendocrine tumor may be helpful for the diagnosis.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Radiology, Nuclear Medicine and imaging,General Medicine

Reference12 articles.

1. [18F]AlF-NOTA-octreotide PET imaging: biodistribution, dosimetry and first comparison with [68Ga]Ga-DOTATATE in neuroendocrine tumour patients;Eur J Nucl Med Mol Imaging,2020

2. 18F-AlF-NOTA-octreotide outperforms 68Ga-DOTA-TATE/-NOC PET in neuroendocrine tumor patients: results from a prospective, multicenter study [published online October 2022];J Nucl Med,2022

3. Clinical application of 18F-AlF-NOTA-octreotide PET/CT in combination with 18F-FDG PET/CT for imaging neuroendocrine neoplasms;Clin Nucl Med,2019

4. 18F-FDG PET/CT and 68Ga-DOTATOC PET/CT in diffuse pancreatic neuroendocrine tumor;Clin Nucl Med,2020

5. Diffuse pancreatic neuroendocrine tumor: a rare presentation;Indian J Nucl Med,2018

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