68Ga-DOTATOC PET in Extracranial Hepatic and Bone Metastasis of Atypical Refractory Meningioma

Author:

Ghomari Cherifa Fazila1,Bender Laura2,Lhermitte Benoît3,Noël Georges,Namer Izzie Jacques,Bund Caroline

Affiliation:

1. Service de Médecine Nucléaire et Imagerie Moléculaire, Institut de Cancérologie Strasbourg Europe, Strasbourg, France

2. Service d’Oncologie Médicale, Institut de Cancérologie Strasbourg Europe, Strasbourg, France

3. Service d’Anatomopathologie, Hôpital de Hautepierre, Hôpitaux Universitaires de Strasbourg, Strasbourg, France

Abstract

Abstract A falcine meningioma was diagnosed in a 66-year-old woman and was treated by surgery and 2 times by radiotherapy during 9 years of follow-up with the diagnosis of atypical meningioma. Three months after the last radiotherapy, incidental liver lesions were detected on chest CT realized for suspected pneumonia. In view of the predisposing factors for meningioma metastases, 68Ga-DOTATOC hepatic and cerebral PET/MRI was performed and completed by total body PET/CT demonstrating a somatostatin receptor 2 overexpression of the multiple liver lesions and several bone lesions. Biopsies from the liver and iliac bone confirmed the metastatic origin of meningioma.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Radiology, Nuclear Medicine and imaging,General Medicine

Reference10 articles.

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4. (68)Ga-DOTANOC PET/CT detection of multiple extracranial localizations in a patient with anaplastic meningioma;Rev Esp Med Nucl Imagen Mol,2015

5. Lung metastases of intracranial atypical meningioma diagnosed on posttherapeutic imaging after 177Lu-DOTATATE therapy;Clin Nucl Med,2018

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