Skeletal “Superscan” With 11C-Methionine PET/CT in Polycythemia Vera

Author:

Jochumsen Mads Ryø,Madsen Michael Alle1,Arveschoug Anne Kirstine1

Affiliation:

1. Department of Nuclear Medicine and PET-Centre, Aarhus University Hospital

Abstract

Abstract 11C-methionine PET/CT for parathyroid adenoma localization on a 60-year-old woman known with polycythemia vera revealed highly methionine-avid red bone marrow, an uptake pattern that has previously been described in hematological disease such as multiple myeloma. An equivalent skeletal “superscan” pattern in polycythemia vera has been described with other PET tracers, but this case illustrates that this pattern can be seen with 11C-methionine PET/CT as well and can be added to the list of potential pitfalls.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Radiology, Nuclear Medicine and imaging,General Medicine

Reference19 articles.

1. Multiple myeloma: molecular imaging with 11C-methionine PET/CT—initial experience;Radiology,2007

2. Skeletal “superscan” on 18F-choline PET/CT: cases of myeloproliferative disease;Clin Nucl Med,2016

3. A polycythemia vera case demonstrated on 18F-choline PET/CT;Rev Esp Med Nucl Imagen Mol (Engl Ed),2021

4. Pitfalls in PSMA-PET/CT: intensive bone marrow uptake in a case with polycythemia vera;Eur J Nucl Med Mol Imaging,2021

5. A pilot study of FDG-PET/CT in polycythemia vera using global analysis techniques;Asia Ocean J Nucl Med Biol,2020

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