Detection of Muscular Metastasis in a Case of Parathyroid Carcinoma Using 18F-FAPI-04 PET/CT

Abstract

Abstract A 46-year-old woman underwent surgery for parathyroid carcinoma 2 years ago. During follow-up, the patient presented with elevated parathyroid hormone (127.50 pg/mL; normal, 15–65). No abnormal uptake of 18F-FDG or 11C-choline was observed on 18F-FDG and 11C-choline PET/CT imaging. The patient was enrolled in a clinical trial for 18F-FAPI PET/CT imaging, revealing a lesion with intense focal uptake within the left sternocleidomastoid muscle. The patient underwent surgery. Postoperative pathology and immunohistochemical analysis confirmed parathyroid carcinoma metastasis.