Chimeric Antigen Receptor T-Cell Therapy of Neurolymphomatosis Monitored by FDG PET/CT

Author:

Li Siqi1,Wang Hongrong2,Wang Guanyun1,Lu Xia1,Yang Jigang1

Affiliation:

1. Department of Nuclear Medicine, Beijing Friendship Hospital of Capital Medical University, Beijing, China

2. Department of Nuclear Medicine, Beijing Boren Hospital, Beijing, China.

Abstract

Abstract 18F-FDG PET/CT was performed to evaluate possible recurrent B-cell lymphoblastic lymphoma in a 34-year-old man. The images showed multiple foci of increased activity in the nerve root and peripheral nerve. A biopsy confirmed the diagnosis of neurolymphomatosis. After receiving chemotherapy, PET/CT showed progressive disease. The patient subsequently received the CD-19 chimeric antigen receptor T-cell therapy. A follow-up PET/CT acquired 30 days after chimeric antigen receptor T-cell therapy revealed no abnormal FDG activity.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Radiology, Nuclear Medicine and imaging,General Medicine

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