18F-FAPI-42 Versus 18F-FDG PET/MRI in a Case of Primary Peripheral T-Cell Lymphoma of the Skeletal Muscles

Author:

Ran Pengcheng1,Li Cheng2,Lv Jieqin1,Liang Xiang1,Dong Aisheng3

Affiliation:

1. Nuclear Medicine, and

2. Hematology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China

3. Department of Nuclear Medicine, The First Affiliated Hospital of Naval Medical University, Shanghai, China.

Abstract

Abstract Primary skeletal muscle lymphoma is rare. We describe 18F-FAPI-42 and 18F-FDG PET/MRI findings in a case of primary peripheral T-cell lymphoma of the skeletal muscles with brain involvement. The multiple skeletal muscle tumors and one larger cerebral tumor showed intense FDG uptake and mild to moderate FAPI uptake. FDG PET was superior to FAPI PET in delineating the muscle tumors because of significantly higher FDG uptake of the muscle tumors than FAPI uptake. FAPI PET was superior to FDG PET in delineating the cerebral lesion because of a very low background FAPI activity in the brain parenchyma.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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