Technique for the Management of Extensive Ocular Surface Lipodermoid Involving the Cornea of Children

Author:

Franco Elena123,Gagrani Meghal1,Lalgudi Vaitheeswaran G.14,Shah Parth R.15,Lenhart Phoebe6,Bhola Rahul7,Nischal Ken K.189

Affiliation:

1. Division of Paediatric Ophthalmology, Strabismus, and Adult Motility, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA;

2. Department of Translational Medicine, University of Ferrara, Ferrara, Italy;

3. Istituto Internazionale per la Ricerca e Formazione in Oftalmologia (IRFO), Forlì, Italy;

4. Department of Cornea and Refractive surgery, University of Ottawa Eye Institute—The Ottawa Hospital, Ottawa, ON, Canada;

5. Department of Ophthalmology, Sydney Children's Hospital, Sydney, Australia;

6. Section of Pediatric Ophthalmology, Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA;

7. Division of Ophthalmology, CHOC Children's Hospital, Orange, CA;

8. Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA; and

9. University of Pittsburgh School of Medicine, Pittsburgh, PA.

Abstract

Purpose: Ocular surface lipodermoids with corneal involvement may require surgical intervention; if deep, ocular surface reconstruction with lamellar corneal tissue or amniotic membrane may be needed. We describe a staged technique using autologous ipsilateral simple limbal epithelial transplantation. Methods: After verifying sparing of Descemet membrane, the conjunctival portion of the lipodermoid was debulked in the first stage. Six weeks later, the corneal portion was excised, followed by autologous ipsilateral simple limbal epithelial transplantation to promote rapid reepithelialization of the residual stromal bed. Temporary tarsorrhaphy was used for patient comfort and to expedite ocular surface healing. Results: Three eyes of 3 children with grade III large ocular surface lipodermoids that encroached the visual axis and hindered proper eyelid closure underwent surgery without complications. In all cases, the visual axis was cleared and eyelid closure was improved. At the last follow-up (mean 35.7 months, median 36.0 months), the bed of the original dermoid showed minimal haze in 1 case, while 2 eyes developed small pseudopterygium; best spectacle–corrected visual acuity improved from 20/200 to 20/70 in the first case, from fix and follow to 20/50 in the second case, and remained fix and follow in the last case, but this child had congenital hydrocephalus with severe developmental delay. Conclusions: This surgical technique is a promising option for children with grade III large ocular surface lipodermoids given its effectiveness in clearing the visual axis and in improving eyelid closure. Moreover, it does not require lamellar corneal transplantation or intervention to the fellow eye.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Ophthalmology

Reference29 articles.

1. New grading system for limbal dermoid: a retrospective analysis of 261 cases over a 10-year period;Zhong;Cornea,2018

2. Prognosis after lamellar keratoplasty for limbal dermoids using preserved corneas;Yamashita;Jpn J Ophthalmol.,2019

3. Preoperative evaluation and outcome of corneal transplantation for limbal dermoids: a ten-year follow-up study;Xin;Int J Ophthalmol.,2016

4. Outcome of lamellar keratoplasty for limbal dermoids in children;Watts;J Am Assoc Pediatr Ophthalmol Strabismus.,2002

5. Surgical management of corneal limbal dermoids: retrospective study of different techniques and use of Mitomycin C;Lang;Eye (Lond).,2014

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