Collagen-Based Artificial Cornea for Lamellar Keratoplasty: An Early Case Report

Author:

Andreev Andrey Yurevich123,Yusef Yusef Naim1,Avetisov Sergey Eduardovich12,Osipyan Grigory Albertovich1,Domogatsky Sergey Petrovich34,Osidak Egor Olegovich35ORCID

Affiliation:

1. Krasnov Research Institute of Eye Diseases, Moscow, Russia;

2. I.M. Sechenov First Moscow State Medical University, Moscow, Russia;

3. Imtek Ltd., Moscow, Russia;

4. FSBI National Medical Research Centre of Cardiology Name after Academician E.I. Chazov of the Ministry of Health of the Russian Federation, Moscow, Russia; and

5. Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia.

Abstract

Purpose: The aim of this study was to evaluate Viscoll collagen membrane (VCM) for lamellar keratoplasty. Methods: A 54-year-old man with grade 4 recurrent pterygium underwent lamellar keratoplasty using VCM as the graft material. Standard keratoplasty postoperative treatments, including topical antibiotic-corticosteroid and artificial tears, were administered. Results: Complete graft epithelialization was achieved after 4 days of the surgery. Follow-up at 9 months showed no pterygium recurrence as well as good integration of the VCM graft into the surrounding tissues with preserved transparency. Conclusions: This case demonstrated that VCM possesses great potential as an alternative to the human donor cornea for lamellar keratoplasty; however, the application of VCM for lamellar keratoplasty still needs additional evaluation.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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