Lymphedema of the Head and Neck—Where Do We Stand and Where We Are Headed

Author:

Taylor Ruby R.1,Pandey Sonia K.2,Smartz Taylor1,Chen Wei F.2,Thaller Seth R.34

Affiliation:

1. School of Medicine, University of Miami Miller, Miami, FL

2. Department of Plastic Surgery, Center for Lymphedema Research and Reconstruction, Cleveland Clinic Foundation, Cleveland, OH

3. DeWitt Daughtry Department of Surgery, Division of Plastic Surgery, School of Medicine, University of Miami Miller

4. DeWitt Daughtry Department of Surgery, Division of Oral and Maxillofacial Surgery, School of Medicine, University of Miami Miller, Miami, FL

Abstract

Great advancements have been made in the management of lymphedema of the extremities with lymphatic surgery. However, lymphedema of other regions, including head and neck, has remained neglected. Recent discovery of lymphatic system in the brain and the communication between intracranial and paracranial lymphatic systems has drawn attention to the head and neck lymphatics. Lymphedema of the head and neck region can result from inherent abnormality of the lymphatic system (primary) or be caused by accidental or iatrogenic injury to lymphatics (secondary). The head and neck contain a large network of lymphatic tissue. They may be affected by direct tumor infiltration, surgical resection of tumors and surrounding cancer tissue, and/or radiotherapy. Proper screening and counseling of patients before facial aesthetic procedures may avoid managing the distress of lymphedema postprocedure. Progression of head and neck lymphedema (HNL) can lead to chronic inflammatory, fibrosclerotic, and fibrofatty deposition, resulting in permanent deformity and disability. Patients may experience functional impairment, including skin changes, pain, range of motion limitations, contracture, dysphagia, dysarthria, dyspnea, and trismus, all leading to reduced quality of life. Despite these known disabilities, HNL is underdiagnosed due to a lack of awareness about this entity and of tools available for measuring internal or external swelling. The authors' article comprehensively reviews the current diagnostic methods and management strategies and what lies ahead.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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