Giant Cell Tumor of the Temporal Bone and Skull Base

Author:

Amoodi Hosam12,Al-Domaidat Derar1,Danish Adel3,Alshaikh Hasan Ro’a4

Affiliation:

1. Otolaryngology Department, Dr. Soliman Fakeeh Hospital, Jeddah, Saudi Arabia

2. Department of Surgery, Jeddah University, Jeddah, Saudi Arabia

3. Department of Pathology

4. Internal Medicine Department, Dr. Soliman Fakeeh Hospital, Jeddah, Saudi Arabia

Abstract

Giant cell tumor (GCT) is a benign tumor that originates from undifferentiated mesenchymal cells of the bone marrow. The craniums as well as temporal bone are extremely rare locations for GCTs. Clinical, radiological, and anatomical diagnosis of this locally aggressive disease poses a major challenge in clinical practice. In this article, we present a clinical study for a 35-year-old female who was found to have left-sided temporal bone GCT with extension to middle cranial fossa and temporomandibular joint (TMJ) with its clinical features and management.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

General Medicine,Otorhinolaryngology,Surgery

Reference9 articles.

1. Giant-cell tumors of the temporal bone: management strategies;Isaacson;Skull Base,2009

2. Invasive giant cell tumor of the lateral skull base: a systematic review, meta-analysis, and case illustration;Freeman;World Neurosurg,2016

3. Giant cell tumor of the temporal bone and skull base: a case report;Kaya;J Int Adv Otology,2018

4. Giant cell tumor of the skull: review of the literature;Tamura;J Neurol Surg A Cent Eur Neurosurg,2016

5. Giant cell bone lesions in the craniofacial region: a diagnostic and therapeutic challenge;Borges;Int Forum Allergy Rhinol,2012

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