Utility of the Repetitive Nerve Stimulation Test and Needle EMG in the Trapezius Muscle for the Early Diagnosis of ALS-Reference-Cited by-同舟云学术

Utility of the Repetitive Nerve Stimulation Test and Needle EMG in the Trapezius Muscle for the Early Diagnosis of ALS

Published:2024-09 Issue:1 Volume:26 Page:1-11
ISSN:1522-0443
Container-title:Journal of Clinical Neuromuscular Disease
language:en
Short-container-title:

Author:

Takahashi Kazusa¹²^ORCID,Hamada Yuichi¹,Kobayashi Masahito³,Kobayashi Shunsuke¹,Kanbayashi Takamichi¹,Hatanaka Yuki¹,Nakayama Takahiro⁴,Imafuku Ichiro⁴,Matsuno Hiromasa⁵,Iguchi Yasuyuki⁵,Katada Fumiaki⁶,Fukutake Toshio⁶,Ando Tetsuo⁶,Mikata Takashi⁷,Usui Toru⁸,Uchino Katsuyuki⁹,Nishiyama Kazutoshi²,Sonoo Masahiro¹^ORCID

Affiliation:

1. Department of Neurology, Teikyo University School of Medicine, Tokyo, Japan;

2. Department of Neurology, Kitasato University School of Medicine, Sagamihara-shi, Kanagawa, Japan;

3. Faculty of Economics, Yokohama National University, Yokohama-shi, Kanagawa, Japan;

4. Department of Neurology, Yokohama Rosai Hospital, Yokohama, Kanagawa, Japan;

5. Department of Neurology, The Jikei University Hospital, Tokyo, Japan;

6. Department of Neurology, Kameda Medical Center, Kamogawa-shi, Kanagawa, Japan;

7. Department of Neurology, Shimoshizu National Hospital and Sanatorium, Yotsukaido-shi, Kanagawa, Japan;

8. Usui Internal Medicine Clinic, Tokyo, Japan; and

9. Kanamachi Station Clinic, Tokyo, Japan.

Abstract

Objectives: To document the utility of decremental responses in the repetitive nerve stimulation test (RNS) and spontaneous activities in needle electromyography (EMG) in the trapezius muscle for the diagnosis of amyotrophic lateral sclerosis. Methods: Subjects were retrospectively identified from our EMG database. Cervical spondylosis was represented as a disease control group. We investigated the sensitivity and specificity of RNS and EMG in the trapezius muscle and those of diagnostic criteria including the Gold Coast criteria (GCC). Results: We reviewed 120 patients with amyotrophic lateral sclerosis and 17 patients with cervical spondylosis. “RNS or EMG” achieved the highest sensitivity (85%). The specificity was the highest for RNS (94%). Addition of RNS of the deltoid muscle achieved 98% sensitivity in the upper-limb onset amyotrophic lateral sclerosis. The sensitivity of the GCC was very high (88%). Conclusions: Neurophysiological parameters investigated in this study having close to 100% specificities or sensitivities are useful as complements to the GCC.

Funder

Ministry of Education, Science, Sports and Culture of Japan

AMED

Publisher

Ovid Technologies (Wolters Kluwer Health)

Reference20 articles.

1. El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis;Brooks;Amyotroph Lateral Scler Other Motor Neuron Disord,2000

2. Electrodiagnostic criteria for diagnosis of ALS;de Carvalho;Clin Neurophysiol,2008

3. Awaji criteria improves the diagnostic sensitivity in amyotrophic lateral sclerosis: a systematic review using individual patient data;Geevasinga;Clin Neurophysiol,2016

4. A proposal for new diagnostic criteria for ALS;Shefner;Clin Neurophysiol,2020

5. Diagnostic utility of Gold Coast criteria in amyotrophic lateral sclerosis;Hannaford;Ann Neurol,2021