Fatty Acid Percentage Distribution in Complex Lipids of Breast Milk From Mothers on a Low Docosahexaenoic Acid Diet-Reference-Cited by-同舟云学术

Fatty Acid Percentage Distribution in Complex Lipids of Breast Milk From Mothers on a Low Docosahexaenoic Acid Diet

Published:2023-03-17 Issue:1 Volume:77 Page:e8-e11
ISSN:0277-2116
Container-title:Journal of Pediatric Gastroenterology & Nutrition
language:en
Short-container-title:

Author:

González Horacio F.¹,Malpeli Agustina¹,Fasano Victoria¹²,Pescio Lucila G.³⁴,Sterin-Speziale Norma B.⁴⁵,Visentin Silvana¹

Affiliation:

1. IDIP – Instituto de Desarrollo e Investigaciones Pediátricas “Prof Dr. Fernando E. Viteri” (Hospital de Niños “Sor María Ludovica” de La Plata, Ministerio de Salud/Comisión de Investigaciones Científicas de la Provincia de Buenos Aires), La Plata, Argentina

2. Departamento de Matemática, Facultad Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina

3. Cátedra de Biología Celular y Molecular, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina

4. IQUIFIB – Instituto de Química y Fisicoquímica Biológicas “Profesor Dr. Alejandro C. Paladini”, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires/Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina

5. Laboratorio Nacional de Investigación y Servicios de Péptidos y Proteínas - Espectrometría de Masa (LANAIS PROEM), Buenos Aires, Argentina.

Abstract

The aim of this study was to assess the fatty acid (FA) percentage distribution in complex lipids of breast milk from mothers on a low docosahexaenoic acid (DHA) diet. We performed a descriptive, cross-sectional study of milk samples (n = 14) collected 90 days after delivery and analyzed them using gas chromatography, thin-layer chromatography, and the Fiske-Subbarow method. Complex lipid distribution was 40.70 ± 5.11% sphingomyelin (SM), 26.03 ± 5.98% phosphatidylethanolamine (PE), 21.12 ± 2.32% phosphatidylcholine, 7.94 ± 1.96% phosphatidylserine, and 4.22 ± 1.25% phosphatidylinositol. Median DHA and arachidonic acid values were 0.13% (0.12; 0.18) and 0.42% (0.33; 0.53), respectively. Mean FA percentage in SM and PE was as follows: palmitic acid, 34.45 ± 1.94% and 5.38 ± 0.94%; oleic acid, 16.50 ± 4.07% and 9.43 ± 4.05%; linoleic acid, 5.91 ± 4.69% and 9.05 ± 4.5%. DHA was not detectable in SM, but it was found in PE (55.33 ± 14.46). In conclusion, breast milk of mothers on a low DHA diet contained 55% DHA in PE, but no DHA in SM.

Publisher

Wiley

Subject

Gastroenterology,Pediatrics, Perinatology and Child Health

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