Affiliation:
1. Department of Pediatric Hematology, Gazi University Faculty of Medicine
2. Department of Pediatric Emergency, Ankara, Turkey
Abstract
We report 2 children with distinct causes of polycythemia, 1 from systemic capillary leak syndrome (SCLS) and the other from protein-losing enteropathy (PLE) caused by CD55 deficiency. There is only a single case series about polycythemia in children with SCLS, but none on polycythemia in children with PLE. We present a 10-year-old girl with hypoalbuminemia, polycythemia, and edema who died as a result of an SCLS attack and a 1-year-old girl with PLE who was successfully treated with eculizumab. Our experience suggests that hematologists should be alert for SCLS and PLE in children with relative polycythemia.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Oncology,Hematology,Pediatrics, Perinatology and Child Health
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