Bevacizumab in the Treatment of Refractory Brain Edema in High-grade Glioma-Reference-Cited by-同舟云学术

Bevacizumab in the Treatment of Refractory Brain Edema in High-grade Glioma

Published:2023-11-30 Issue:1 Volume:46 Page:e87-e90
ISSN:1077-4114
Container-title:Journal of Pediatric Hematology/Oncology
language:en
Short-container-title:

Author:

Alsahlawi Aysha K.¹,Michaud-Couture Claudie²,Lachance Alexandre²,Bergeron-Gravel Samuel³,Létourneau Mélanie³,Bourget Catherine⁴,Gould Peter V.⁵,Giannakouros Panagiota⁶,Nakada Emily M.⁷,Faury Damien⁷,Crevier Louis⁸,Bouffet Éric⁹¹⁰,Jabado Nada⁷,Larouche Valérie⁶,Renzi Samuele⁶

Affiliation:

1. Department of Neurological Surgery, McGill University, Montreal, Canada

2. Faculty of Medicine, Université Laval, Quebec, Canada

3. Division of Radiation Oncology, CHU de Québec - Université Laval, Quebec, Canada

4. Department of Diagnostic Radiology, CHU de Québec - Université Laval, Quebec, Canada

5. Division of Molecular Biology, Medical Biochemistry and Pathology, CHU de Québec - Université Laval, Quebec, Canada

6. Department of Pediatrics, Division of Hemato-Oncology, CHU de Québec-Université Laval, Quebec, Canada

7. Department of Pediatrics, McGill University, and The Research Institute of the McGill University Health Centre, Montreal, Canada

8. Division of Neurosurgery, Department of Surgery, CHU de Québec - Université Laval, Quebec, Canada

9. The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada

10. Division of Haematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada

Abstract

We report the case of a 14-year-old boy with a steroid-dependent refractory tumor whose longstanding dexamethasone treatment was successfully discontinued after a course of bevacizumab. The use of bevacizumab despite the absence of clear evidence of radionecrosis allowed a significant decrease in the amount of the brain edema.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Oncology,Hematology,Pediatrics, Perinatology and Child Health

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