Heart–Lung Transplantation From Donation After Circulatory Death Using Mobile Normothermic Regional Perfusion

Author:

Spencer Philip J.1,Saddoughi Sahar A.1ORCID,Choi Kukbin1ORCID,Dickinson Timothy A.1,Richman Adam1,Reynolds F. Alex1,Villavicencio Mauricio A.1ORCID

Affiliation:

1. From the Department of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota.

Abstract

Combined heart-lung transplant (HTLx) is the most durable treatment available for end-stage heart and lung failure. Many patients are unable to receive combined organs due to organ availability and allocation policies prioritizing separate heart or lung transplantation. While an average of 45 HTLxs have been performed per year in the United States half the listed patients do not receive organs. Recently, donation after circulatory death (DCD) utilizing normothermic regional perfusion (NRP) has been utilized for heart allografts with excellent results, and here, we present a case utilizing mobile NRP to procure a heart and lung block from a circulatory death donor and successful implantation for a recipient in a separate center.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Biomedical Engineering,General Medicine,Biomaterials,Bioengineering,Biophysics

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