Predicting Hemodynamic Changes During Intra-Aortic Balloon Pump Support With a Longitudinal Evaluation

Author:

Castagna Francesco1ORCID,Viswanathan Shankar2,Chalhoub George1,Ippolito Paul1,Ovalle Ramos Julio Andres1,Vukelic Sasa1,Sims Daniel B.1,Madan Shivank1,Saeed Omar1,Jorde Ulrich P.1

Affiliation:

1. Division of Cardiology, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, New York

2. Department of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, New York.

Abstract

The use of intra-aortic balloon pump (IABP) has decreased in recent years due to negative outcome studies in cardiogenic shock complicating acute myocardial infarction, despite its favorable adverse-event profile. Acute hemodynamic response studies have identified potential super-responders with immediate improvements in cardiac index (CI) in heart failure patients. This single-center retrospective study aimed to predict CI and mean arterial pressure (MAP) changes throughout the entire duration of IABP support. The study analyzed 336 patients who received IABP between 2016 and 2022. Linear mixed-effect regression models were used to predict CI and MAP improvement during IABP support. The results showed that CI and MAP increases during the first days of support, and changes during IABP support varied with time and were associated with baseline parameters. Longitudinal CI change was associated with body surface area, baseline CI, baseline pulmonary artery pulsatility index, baseline need for pressors, and diabetes. Longitudinal MAP change was associated with baseline MAP, baseline heart rate, need for pressors, or inotropes. The study recommends considering these parameters when deciding if IABP is the most appropriate form of support for a specific patient. Further prospective studies are needed to validate the findings.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Biomedical Engineering,General Medicine,Biomaterials,Bioengineering,Biophysics

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Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Contemporary approach to cardiogenic shock care: a state-of-the-art review;Frontiers in Cardiovascular Medicine;2024-03-13

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