Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses-Reference-Cited by-同舟云学术

Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses

Published:2002-04 Issue:3 Volume:12 Page:183-190
ISSN:0960-314X
Container-title:Pharmacogenetics
language:en
Short-container-title:Pharmacogenetics

Author:

Urano Wako,Taniguchi Atsuo,Yamanaka Hisashi,Tanaka Eiichi,Nakajima Hiroshi,Matsuda Yuko,Akama Hideto,Kitamura Yutaka,Kamatani Naoyuki

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

General Pharmacology, Toxicology and Pharmaceutics,Genetics

Reference22 articles.

1. Methotrexate in rheumatoid arthritis

2. The comparative efficacy and toxicity of second-line drugs in rheumatoid arthritis results of two metaanalyses

3. The Pharmacology and Clinical Use of Methotrexate

4. Methotrexate-resistant Variants of Human Dihydrofolate Reductase with Substitutions of Leucine 22

5. The effects of leucovorin (folinic acid) on methotrexate therapy in rheumatoid arthritis patients

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1. Impact of MTHFR gene polymorphism on the outcome of methotrexate treatment in a sample of Iraqi rheumatoid arthritis patients;Scientific Reports;2024-07-02

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4. MTHFR Gene Polymorphism Association With Psoriatic Arthritis Risk and the Efficacy and Hepatotoxicity of Methotrexate in Psoriasis;Frontiers in Medicine;2022-04-11

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