Phase I and pharmacokinetic study of the orally administered farnesyl transferase inhibitor R115777 in patients with advanced solid tumors-Reference-Cited by-同舟云学术

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Phase I and pharmacokinetic study of the orally administered farnesyl transferase inhibitor R115777 in patients with advanced solid tumors

Published:2001-03 Issue:3 Volume:12 Page:193-197
ISSN:0959-4973
Container-title:Anti-Cancer Drugs
language:en
Short-container-title:Anti-Cancer Drugs

Author:

Punt C JA,van Maanen L,Bol C JJG,Seifert W F,Wagener D JTh

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cancer Research,Pharmacology (medical),Pharmacology,Oncology

Reference7 articles.

1. Regulators and Effectors of ras Proteins

2. Resistance of K-RasBV12 proteins to farnesyltransferase inhibitors in Rat1 cells.

3. Direct Demonstration of Geranylgeranylation and Farnesylation of Ki-Ras in Vivo

4. K- and N-Ras Are Geranylgeranylated in Cells Treated with Farnesyl Protein Transferase Inhibitors

5. Cell Growth Inhibition by Farnesyltransferase Inhibitors Is Mediated by Gain of Geranylgeranylated RhoB

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1. Farnesyl Transferase Inhibitors as Potential Anticancer Agents;Mini-Reviews in Medicinal Chemistry;2018-10-12

2. A phase I study of the farnesyltransferase inhibitor Tipifarnib in combination with the epidermal growth factor tyrosine kinase inhibitor Erlotinib in patients with advanced solid tumors;Investigational New Drugs;2018-08-31

3. Targeted Therapy for Medullary Thyroid Cancer: A Review;Frontiers in Oncology;2017-10-06

4. Phase 2 randomized, flexible crossover, double-blinded, placebo-controlled trial of the farnesyltransferase inhibitor tipifarnib in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas;Neuro-Oncology;2014-02-04

5. The role of the farnesyltransferase inhibitor lonafarnib in the treatment of Progeria;Expert Opinion on Orphan Drugs;2013-12-13

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