The homocamptothecin BN 80915 is a highly potent orally active topoisomerase I poison-Reference-Cited by-同舟云学术

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The homocamptothecin BN 80915 is a highly potent orally active topoisomerase I poison

Published:2001-01 Issue:1 Volume:12 Page:9-19
ISSN:0959-4973
Container-title:Anti-Cancer Drugs
language:en
Short-container-title:Anti-Cancer Drugs

Author:

Demarquay Danièle,Huchet Marion,Coulomb Helène,Lesueur-Ginot Laurence,Lavergne Olivier,Kasprzyk Philip G,Bailly Christian,Camara Jose,Bigg Dennis CH

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cancer Research,Pharmacology (medical),Pharmacology,Oncology

Reference41 articles.

1. DNA topoisomerase I: customs officer at the border between DNA and RNA worlds?

2. Topoisomerase enzymes as drug targets

3. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.

4. Topoisomerase I inhibitors: Review and update

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1. The recent developments of camptothecin and its derivatives as potential anti-tumor agents;European Journal of Medicinal Chemistry;2023-11

2. Design and synthesis of novel 20(S)-α-aminophosphonate derivatives of camptothecin as potent antitumor agents;Bioorganic Chemistry;2021-09

3. Synthetic DNA‐Targeted Chemotherapeutic Agents And Related Tumor‐Activated Prodrugs;Burger's Medicinal Chemistry and Drug Discovery;2021-04-26

4. Synthesis of Novel Pyrazole Derivatives as Promising DNA-Binding Agents and Evaluation of Antitumor and Antitopoisomerases I/II Activities;Chemical and Pharmaceutical Bulletin;2018-11-01

5. Design, semisynthesis and potent cytotoxic activity of novel 10-fluorocamptothecin derivatives;Bioorganic & Medicinal Chemistry Letters;2017-10

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