Intrathecal 2-Chloroprocaine 3% Versus Hyperbaric Bupivacaine 0.75% for Cervical Cerclage: A Double-blind Randomized Controlled Trial

Abstract

(Anesth Analg. 2022;134:634–632) Cervical cerclage, an operation designed to reduce preterm delivery and improve perinatal outcomes, is often performed under spinal anesthesia. While the benefits of spinal anesthesia are well documented, a short-acting local anesthetic agent, such as 2-chloroprocaine, could shorten postanesthesia care unit (PACU) stay compared with longer acting agents. Currently, bupivacaine is the most used local anesthesia for cerclage because of historical concern regarding 2-chloroprocaine’s safety. This study randomly compared the outcome of 2-chloroprocaine 3% 50 mg and hyperbaric bupivacaine 0.75% 9 mg on dermatomal level, sensory block resolution, ability to ambulate and void, and motor blockade.