Fibrinolysis shutdown is associated with a fivefold increase in mortality in trauma patients lacking hypersensitivity to tissue plasminogen activator

Author:

Moore Hunter B.,Moore Ernest E.,Huebner Benjamin R.,Dzieciatkowska Monika,Stettler Gregory R.,Nunns Geoffrey R.,Lawson Peter J.,Ghasabyan Arsen,Chandler James,Banerjee Anirban,Silliman Christopher,Sauaia Angela,Hansen Kirk C.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Critical Care and Intensive Care Medicine,Surgery

Reference34 articles.

1. The Fibrinolytic Mechanism in Haemostasis: A Review;J Clin Pathol,1964

2. Hyperfibrinolysis, physiologic fibrinolysis, and fibrinolysis shutdown: the spectrum of postinjury fibrinolysis and relevance to antifibrinolytic therapy;J Trauma Acute Care Surg,2014

3. Acute fibrinolysis shutdown after injury occurs frequently and increases mortality: a multicenter evaluation of 2,540 severely injured patients;J Am Coll Surg,2016

4. Abnormalities in fibrinolysis at the time of admission are associated with DVT, mortality and disability in a pediatric trauma population;J Trauma Acute Care Surg,2016

5. Influence of fibrinolysin on shock;JAMA,1963

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