Neutron Activation Analysis Based on AB-BNCT Treatment Room

Author:

Cai Yunzhu1,Gu Shaoxian1,Wang Ningyu2,Cui Fengjie3,Liu Wei1,Li Tianhang1,Wu Zhangwen1,Gou Chengjun1

Affiliation:

1. Key Laboratory of Radiation Physics and Technology of Ministry of Education, Institute of Nuclear Science and Technology, Sichuan University, Chengdu 610064, China

2. Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China

3. Department of Radiation Oncology, Qilu Hospital of Shandong University Dezhou Hospital, Dezhou 253000, China.

Abstract

Abstract Boron neutron capture therapy (BNCT) is an ideal binary targeted radiotherapy for treating refractory tumors. An accelerator-based BNCT (AB-BNCT) neutron source has attracted more and more attention due to its advantages such as higher neutron yield in the keV energy region, less gamma radiation, and higher safety. In addition to 10B, neutrons also react with other elements in the treatment room during BNCT to produce many activation products. Due to the long half-life of some activation products, there will be residual radiation after the end of treatment and the shutdown of the accelerator, which has adverse effects on radiation workers. Therefore, the ambient dose equivalent rate in the treatment room needs to be evaluated. The AB-BNCT neutron source model proposed by Li is studied in this paper. Based on the Monte Carlo method, the Geant4 platform was used to simulate the dose induced by radionuclides near the Beam Shaping Assembly (BSA) of the source. It is concluded that the concrete wall contributed the most to the radiation dose. The dose rate of 2.45 μSv h−1 after 13 min of shutdown meets the dose rate limit of 2.5 μSv h−1, at which point it is safe for workers to enter the treatment room area.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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